804 The Role of Kono-S Anastomosis and Mesenteric Resection in Reducing Recurrence After Surgery for Crohn’s Disease: A Systematic Review

Abstract Aim Recurrence after surgery for Crohn’s disease is common. Anastomotic configuration may influence recurrence and the mesentery be key.The Kono-S anastomosis radical mesenteric excision have been proposed as methods of reducing recurrence. We analysed literature pertaining to these novel techniques. Method searched MEDLINE, Embase Cochrane Library for, studies evaluating and/or in disease. assessed methodological quality risk bias using tool randomized controlled trials JBI nonrandomized trials. A narrative synthesis was used summarize findings. Results Nine (896 patients) were identified. Apart from one trial with a low overall level evidence poor (Grade IV). The associated lower incidence endoscopic surgical (0%–3.4% vs 15%–24.4% respectively). Complications, particularly anastomotic leak rate, also (1.8% 9.3% Evidence single poor-quality study suggested that reduce rates compared preservation. Conclusions existing suggests safe recurrence, but mainly poor. One element technique, preservation mesentery, detrimental Further, higher quality, are required investigate Such should consider impact degree resection addition on